The teacher-searchers

Agri-food and Nutrition Sciences Department

• Digestive physiology
• Microbiology

Health of the microbiota / gut / brain axis

Head of the Neuro-Gastroenterology and Nutrition (NGN) team, Joint Research Unit UMR 1331 Toxalim (Food Toxicology), INRAE (National Agricultural, Food and Environment Research Institute), University of Toulouse, ENVT (Toulouse National Veterinary School), INP-PURPAN, UPS (University of Toulouse Paul Sabatier)

• Accreditation to Supervise Research, INP Toulouse
• PhD in Digestive Physio-pathology and Pharmacology, INRA (National Agricultural Research Institute) Pharmacology Unit & University of Toulouse
• Certification in animal experimentation, designer level, ENVT (Toulouse National Veterinary School)
• Diploma in experimental surgery, ENV Nantes Veterinary School

Scientific subjects of interest:

• Bidirectional communication of the microbiota/gut/brain axis.
• Evaluation of the mechanisms of action of probiotic strains, postbiotics, fermented foods and bioactive nutritional compounds (impact on gut health in the neonatal period and in adulthood).
• Exploring dietary remediation in anxiety and stress disorders. Visceral pain, Digestive well-being
• In vivo pathophysiological approaches in models mimicking human pathologies such as irritable bowel syndrome.

Project management:

• Coordinator of academic research projects (ANR, ITN Marie Curie, Regional projects, Carnot) and finalized projects (Lesaffre, Danone, Nestec, Noventure, Rosell Institute Lallemand, etc.)
• Active participation in the strategy of Occitania’s academic and industrial networks.
• Scientific advice and analysis for manufacturers (Danone, Nestec, Noventure, Heel, etc.).
• Patent registration with operating license and research contract.

https://pubmed.ncbi.nlm.nih.gov/?term=eutamene+h

• Lactococcus lactis CNCM I-5388 versus NCDO2118 by its GABA hyperproduction ability, counteracts faster stress-induced intestinal hypersensitivity in rats. Gomes P, Laroute V, Beaufrand C, Daveran-Mingot ML, Aubry N, Liebgott C, Ballet N, Legrain-Raspaud S, Theodorou V, Mercier-Bonin M, Cocaign-Bousquet M, Eutamene H. FASEB J. 2023 Nov;37(11):e23264. doi: 10.1096/fj.202301588R.
• Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rats via GABA production in the gastrointestinal tract. Laroute V, Beaufrand C, Gomes P, Nouaille S, Tondereau V, Daveran-Mingot ML, Theodorou V, Eutamene H, Mercier-Bonin M, Cocaign-Bousquet M. Elife. 2022 Jun 21;11:e77100. doi: 10.7554/eLife.77100.
• Increased fermentable carbohydrate intake alters colonic mucus barrier function through glycation processes and increased mast cell counts. Kamphuis JBJ, Reber L, Eutamène H, Theodorou V. FASEB J. 2022 May;36(5):e22297. doi: 10.1096/fj.202100494RRR.
• Human milk oligosaccharides alleviate stress-induced visceral hypersensitivity and associated microbiota dysbiosis. Ferrier L, Eutamène H, Siegwald L, Marquard AM, Tondereau V, Chevalier J, Jacot GE, Favre L, Theodorou V, Vicario M, Rytz A, Bergonzelli G, Garcia-Rodenas CL. J Nutr Biochem. 2022 Jan;99:108865. doi: 10.1016/j.jnutbio.2021.108865.
• Lactose and Fructo-oligosaccharides Increase Visceral Sensitivity in Mice via Glycation Processes, Increasing Mast Cell Density in Colonic Mucosa. Kamphuis JBJ, Guiard B, Leveque M, Olier M, Jouanin I, Yvon S, Tondereau V, Rivière P, Guéraud F, Chevolleau S, Noguer-Meireles MH, Martin JF, Debrauwer L, Eutamène H, Theodorou V. Gastroenterology. 2020 Feb;158(3):652-663.e6. doi: 10.1053/j.gastro.2019.10.037.

UMR 1331 Toxalim (Food Toxicology), INRAE (National Agricultural, Food and Environment Research Institute), University of Toulouse, ENVT (Toulouse National Veterinary School), INP-PURPAN, UPS (University of Toulouse Paul Sabatier)